133) Kushal Vanamala, Ketki Bhise, Hiram Sanchez, Razieh Kebriaei, Duy Luong, Samaresh Sau, Hosam Abdelhady, Michael J. Rybak, David Andes. Arun K. Iyer*. Folate Functionalized Lipid Nanoparticles for Targeted Therapy of Methicillin-Resistant Staphylococcus aureus. Pharmaceutics 2021 (13)11:10.3390 (available for download online: 10.3390/pharmaceutics13111791).
132) Ketki Bhise, Samaresh Sau, Rami Alzhrani, Mohd A Rauf, Katyayani Tatiparti, Arun K Iyer*. Imaging the cellular components of the immune system for advancing diagnosis and immunotherapy of cancers. Materials Today Advances 2021: 10, 100138.
131) Shriya Reddy, Katyayani Tatiaparti, Samaresh Sau, Arun K Iyer*. Recent advances in nano delivery systems for blood-brain barrier (BBB) penetration and targeting of brain tumors. Drug Discovery Today 2021. (Online).
130) Tejaswi Koneru, Eva McCord, Shreya Pawar, Katyayani Tatiparti, Samaresh Sau, Arun K Iyer*. Transferrin: Biology and Use in Receptor-Targeted Nanotherapy of Gliomas. ACS Omega, 2021: 6(13), 8727–8733.
129) Shreya Pawar, Tejaswi Koneru, Eva McCord, Katyayani Tatiparti, Samaresh Sau, Arun K Iyer*. LDL receptors and their role in targeted therapy for glioma: a review. Drug Discovery Today 2021. (Online).
128) Eva McCord, Shreya Pawar, Tejaswi Koneru, Katyayani Tatiparti, Samaresh Sau, Arun K Iyer*. Folate Receptors’ Expression in Gliomas May Possess Potential Nanoparticle-Based Drug Delivery Opportunities. ACS Omega, 2021: 6(6), 4111–4118.
127) Priyanka Bose, Amit K Harit, Ratnesh Das, Samaresh Sau, Arun K Iyer, Sushil K Kashaw. Tuberculosis: current scenario, drug targets, and future prospects. Medicinal Chemistry Research, Springer, USA, 2021: 1-27.
126) Mohd Ahmar Rauf, Munazzah Tasleem, Ketki Bhise, Katyayani Tatiparti, Samaresh Sau, Arun K. Iyer*. Nano‐therapeutic strategies to target coronavirus. View, 2021: 20200155.
125) Ghazal Nabil, Rami Alzhrani, Hashem O Alsaab, Mohammed Atef, Samaresh Sau, Arun K Iyer, Hossny El Banna. CD44 Targeted Nanomaterials for Treatment of Triple-Negative Breast Cancer. Cancers, 2021: 13(4), 898.
124) Mohammad Oves, Mohd Ahmar Rauf, Fohad Mabood Husain, Mohammad Zubair, Iqbal MI Ismail, Arun Iyer. Fungal Infection: The Hidden Enemy? Diabetic Foot Ulcer, Springer, Singapore, 2021: 161-176.
123) Arun Iyer, Madeleine Frank, Susan Davies, William T Gelson. Mycophenolate mofetil-induced liver injury in a patient with aquaporin-4 antibody positive transverse myelitis. BMJ Case Reports CP 2020: 13(12), e238345.
122) Mohammad Oves, Mithunan Ravindran, Mohd Ahmar Rauf, Mohammad Omaish Ansari, Maryam Zahin, Arun K Iyer, Iqbal MI Ismail, Meraj A Khan, Nades Palaniyar. Comparing and Contrasting MERS, SARS-CoV, and SARS-CoV-2: Prevention, Transmission, Management, and Vaccine Development. Pathogens 2020: 9(12), 985.
121) Kushal Vanamala, Katyayani Tatiparti, Ketki Bhise, Samaresh Sau, Marc H Scheetz, Michael J Rybak, David Andes, Arun K. Iyer*. Novel Approaches for the Treatment of Methicillin-Resistant Staphylococcus aureus: Using Nanoparticles to Overcome Multidrug Resistance. Drug Discovery Today 2021: 26(1), 31-43.
120) Katyayani Tatiparti, Samaresh Sau, Mohd Ahmar Rauf, Arun K. Iyer*. Smart treatment strategies for alleviating tauopathy and neuroinflammation to improve clinical outcome in Alzheimer's disease. Drug Discovery Today, 2020: 25(12), 2110-2129.
119) Hashem O Alsaab, Maha S Alghamdi, Albatool S Alotaibi, Rami Alzhrani, Fatimah Alwuthaynani, Yusuf S Althobaiti, Atiah H Almalki, Samaresh Sau, Arun K Iyer*. Progress in Clinical Trials of Photodynamic Therapy for Solid Tumors and the Role of Nanomedicine. Cancers, 2020: 12 (10), 2793.
118) Mohd Ahmar Rauf, Katyayani Tatiparti, Samaresh Sau, Arun K. Iyer*. Hypoxia penetrating ultra-small nanoparticle for anti-cancer effect in Glioblastoma. Cancer Research, 2020: 80 (16 Supplement), 1721-1721.
117) Kushal Vanamala, Samaresh Sau, Shivani Naik, Arun K. Rishi, Arun K. Iyer*. Tumor multicomponent targeting nanoparticle for synergistic killing of drug resistant renal cell carcinoma. Cancer Research, 2020: 80 (16 Supplement), 2618-2618.
116) Ketki Bhise, Samaresh Sau, Mohd Ahmar Rauf, Arun K. Rishi, Arun K. Iyer*. Hypoxia-targeting prodrug approach for multimodal chemotherapy and immunogenic cell death in aggressive triple negative breast cancer. Cancer Research, 2020: 80 (16 Supplement), 6263-6263.
115) Mohammad Oves, Mohd Rauf, Mohammad Omaish Ansari, Aftab Aslam Parwaz Khan, Huda A Qari, Mohamed F Alajmi, Samaresh Sau, Arun K Iyer*. Graphene Decorated Zinc Oxide and Curcumin to Disinfect the Methicillin-Resistant Staphylococcus aureus. Nanomaterials, 2020: 10 (8), 1453.
114) Ketki Bhise, Samaresh Sau, Mohd Ahmar Rauf, Rami Alzhrani, Arun K. Iyer*. Hypoxia Targeting Nanoparticles for Immunogenic Cell Death of Triple Negative Breast Cancer. The FASEB Journal, 2020: 34 (S1), 1-1.
113) Katyayani Tatiparti, Mohd Ahmar Rauf, Samaresh Sau, Arun K. Iyer*. Carbonic Anhydrase-IX Guided Albumin Nanoparticles for Hypoxia-mediated Triple-Negative Breast Cancer Cell Killing and Imaging of Patient-derived Tumor. Molecules, 2020: 25 (10), 2362.
112) Katyayani Tatiparti, Mohd Ahmar Rauf, Samaresh Sau, Rami Alzhrani, Arun Iyer*. Ultra‐Small Biomimetic Nanoparticles for Alzheimer’s Disease Targeted Drug Delivery. The FASEB Journal, 2020: 34 (S1), 1-1.
111) Rami Alzhrani, Samaresh Sau, Amro Aboukameel, Hashem Alsaab, Asfar Azmi, Arun Iyer*. Tumor Stroma Targeting Nanoparticles Pro‐drug Approach for Treating Pancreatic Ductal Adenocarcinoma. The FASEB Journal, 2020: 34 (S1), 1-1.
110) Mehdi Azizi, Hassan Dianat‐Moghadam, Roya Salehi, Masoud Farshbaf, Disha Iyengar, Samaresh Sau, Arun K Iyer, Hadi Valizadeh, Mohammad Mehrmohammadi, Michael R Hamblin. Interactions Between Tumor Biology and Targeted Nanoplatforms for Imaging Applications. Advanced Functional Materials, 2020: 30 (19), 1910402.
109) Sushil K Kashaw, Prashant Sahu, Vaibhav Rajoriya, Pradeep Jana, Varsha Kashaw, Samaresh Sau, Arun K Iyer*. Exploring siRNA Umpired Nanogels: A Tale of Barrier Combating Carrier. Current Pharmaceutical Design, 2020:
108) Katyayani Tatiparti, Mohd Ahmar Rauf, Samaresh Sau, Arun K. Iyer*. A Biomimetic Drug Delivery System Targeting Tumor Hypoxia in Triple-Negative Breast Cancers. Applied Sciences, 2020: 10(3), 1075.
107) Ketki Bhise, Samaresh Sau, Rami Alzhrani, Arun K Iyer*. Nanoparticles for Immune Cell Reprogramming and Reengineering of Tumor Microenvironment. Cell Reprogramming for Immunotherapy, Humana, New York, NY, 2020: 211-221.
106) Prashant Sahu, Sushil K Kashaw, Samaresh Sau, Varun Kushwah, Sanyog Jain, Arun K Iyer*. Discovering pH triggered charge rebound surface modulated topical nanotherapy against aggressive skin papilloma. Materials Science and Engineering: C, 2019: 107, 110263.
105) Rami Alzhrani, Hashem O Alsaab, Alex Petrovici, Ketki Bhise, Kushal Vanamala, Samaresh Sau, Matthew J Krinock, Arun K Iyer*. Improving the therapeutic efficiency of noncoding RNAs in cancers using targeted drug delivery systems. Drug Discovery Today, 2020: 25 (4), 718-730
104) Samaresh Sau, Prashant Sahu, Sushil K. Kashaw, Arun K. Iyer. Multitasking Role of Dendrimers: Drug Delivery and Disease Targeting. Nanomedicine for the Treatment of Disease: From Concept to Application, CRC Press, 2019: 17-32.
103) Priya Singh, Mitali Mishra, Shivangi Agarwal, Samaresh Sau, Arun K Iyer, Sushil K Kashaw. Exploring the Role of Water Molecules in the Ligand Binding Domain of PDE4B and PDE4D: Virtual Screening Based Molecular Docking of Some Active Scaffolds. Current computer-aided drug design, 2019: Volume 15 (4), 334-366
102) Prashant Sahu, Sushil K Kashaw, Samaresh Sau, Varun Kushwah, Sanyog Jain, Ram K Agrawal, Arun K Iyer*. pH triggered and charge attracted nanogel for simultaneous evaluation of penetration and toxicity against skin cancer: In-vitro and ex-vivo study. International Journal of Biological Macromolecules, 2019: 128, 740-751.
101) Samaresh Sau, Rami Alzhrani, Ketki Bhise, Hashem O Alsaab, Sushil K Kashaw, Arun K Iyer*. Nanomaterials for tumor immunomodulation and overcoming current clinical challenges. Nanomedicine, 2019: (1743-5889), 14 (12), 1515.
100) Samaresh Sau, Alex Petrovici, Hashem O Alsaab, Ketki Bhise, Arun K Iyer*. PDL-1 antibody drug conjugate for selective chemo-guided immune modulation of cancer. Cancers, 2019: 11 (2), 232.
99) Prashant Sahu, Sushil K Kashaw, Samaresh Sau, Varun Kushwah, Sanyog Jain, Ram K Agrawal, Arun K Iyer*. pH Responsive 5-Fluorouracil Loaded Biocompatible Nanogels For Topical Chemotherapy of Aggressive Melanoma. Colloids and Surfaces B: Biointerfaces, 2019: 174, 232-245.
98) Sushil K Kashaw, Shivangi Agarwal, Mitali Mishra, Samaresh Sau, Arun K Iyer*. Molecular Docking Analysis of Caspase-3 Activators as Potential Anticancer Agents. Current Computer-Aided Drug Design, 2019: 15 (1), 55-66.
97) Ghazal Nabil, Ketki Bhise, Samaresh Sau, Mohamed Atef, Hossny A El-Banna, Arun K Iyer*. Nano-engineered delivery systems for cancer imaging and therapy: Recent advances, future direction and patent evaluation. Drug Discovery Today, 2019: 24 (2), 462-491.
96) Prashant Sahu, Sushil K Kashaw, Samaresh Sau, Arun K Iyer. Polylactide-co-glycolide-based Nanogel: Concept and Functions. Materials for Biomedical Engineering, Elsevier, 2019: 399-423.
95) Hashem O Alsaab, Rami Alzhrani, Atiah H Almalki, Yusuf S Althobaiti, Samaresh Sau, Arun K Iyer. Imaging tools to enhance animal tumor models for cancer research and drug discovery. Animal Models in Cancer Drug Discovery, Academic Press, 2019: 75-106.
94) Samaresh Sau and Arun K Iyer*. Immunotherapy and molecular role of T-cell in PD-1 antibody treated resectable lung cancer patients. Journal of Thoracic Disease, 2018: 10(8), 4682-4685.
93) Hashem O. Alsaab, Samaresh Sau, Rami M. Alzhrani, Vino T. Cheriyan, Lisa A. Polin, Ulka Vaishampayan, Arun K. Rishi, Arun K. Iyer*. Tumor Hypoxia Directed Multimodal Nanotherapy for Overcoming Drug Resistance in Renal Cell Carcinoma and Reprogramming Macrophages. Biomaterials 2018: 183, 280-294. (*Corresponding author).(Available online)
92) Ghazal Nabil, Ketki Bhise, Samaresh Sau, Mohamed Atef, Hossny A. El-Banna, Arun K. Iyer*. Nanoengineered delivery systems for cancer imaging and therapy: recent advances, future directions and patent evaluation. Drug Discovery Today (2018) Accepted, in press. (*Corresponding Author). (Available online)
91) Ketki Bhise, Samaresh Sau, Razieh Kebriaei, Seth A Rice, Kyle C Stamper, Hashem O Alsaab, Michael J Rybak, Arun K Iyer. Combination of Vancomycin and Cefazolin Lipid Nanoparticles for Overcoming Antibiotic Resistance of MRSA. Materials 2018. (Available online)
90) Vino Cheriyan, Hashem Alsaab, Sreeja Sekhar, Jaganathan Venkatesh, Arindam Mondal, Imran Vhora, Samaresh Sau, Magesh Muthu, Lisa Polin, Edi Levi, Gerold Bepler, Arun Iyer, Mandip Singh, Arun Rishi. A Carp-1 Functional Mimetic Compound is Synergistic with braf-Targeting in Non-Small Cell Lung Cancers. Oncotarget (Accepted, in press).(Available online)
89) Zhaoxian Wang, Samaresh Sau, Hashem O. Alsaab, Arun K. Iyer*. Image-Guided Therapy of Triple Negative Breast Cancer using CD44 Directed Delivery of Biocompatible Nanomicelles. Nanomedicne: NBM, 2018 (*Corresponding author). (Available online)
88) Samaresh Sau* ,HashemO.Alsaab, KetkiBhise, Rami Alzhrani, Ghazal Nabil , and Arun K.Iyer*. Multifunctional nanoparticles for cancer immunotherapy: A groundbreaking approach for reprogramming malfunctioned tumor evironment. Journal of Controlled Release, 2018 (*Corresponding author).(Available online)
87) Samaresh Sau* , Katyayani Tatiparti, Hashem O. Alsaab, Sushil K. Kashaw, and Arun K. Iyer*. A tumor multicomponent targeting chemoimmune drug delivery system for reprograming the tumor microenvironment and personalized cancer therapy. Drug Discovery Today, 2018 (*Corresponding author).(Available online)
86) Shivangi Agarwal, Ekta Verma, Vivek Kumar, Namrita Lall, Samaresh Sau, Arun K. Iyer, Sushil K. Kashaw. An integrated computational approach of molecular dynamics simulations, receptor binding studies and pharmacophore mapping analysis in search of potent inhibitors against tuberculosis. Journal of Molecular Graphics and Modelling, 2018. (Available online)
85) Vino T. Cheriyan, Hashem Alsaab, Sreeja Sekhar, Caitlin Stieber, Prashant Kesharwani, Samaresh Sau, Magesh Muthu, Lisa A. Polin, Edi Levi, Arun k. Iyer* and Arun K. Rishi*. A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of Renal Cell Carcinoma. Oncotarget, 2017 (*Corresponding Author).(Available online)
84) Katyayani Tatiparti, Samaresh Sau* , Kaustubh A. Gawde, and Arun K. Iyer* . Copper-Free ‘Click’ Chemistry-Based Synthesis and Characterization of Carbonic Anhydrase-IX Anchored Albumin-Paclitaxel Nanoparticles for Targeting Tumor Hypoxia. International Journal of Molecular Sciences. 2018. (*Corresponding author) (Available online)
83) Hashem Alsaab, Samaresh Sau*, Rami Alzharani, Katyayani Tatiparti, Ketki Bhise, Sushil K. Kashaw and Arun K. Iyer*. PD-1 and PD-L1 checkpoint signaling inhibition for cancer immunotherapy: mechanism, combinations and clinical outcome. Frontiers in Pharmacology. 2017, 8:561 . (*Corresponding Author).(Available online)
82) Kaustubh Gawde, Samaresh Sau, Katyayani Tatiparti, Sushil Kashaw, Mohammad Mehrohammadi, Asfar S. Azim and Arun K. Iyer*. Paclitaxel and Di-fluorinated Curcumin Loaded in Albumin Nanoparticles for Targeted Synergistic Combination Therapy of Ovarian and Cervical Cancers. Colloids and Surfaces B: Bionterfaces (2018) (*Corresponding Author) (Available online)
81) Ketki Bhise, Samaresh Sau, Hashem Alsaab, Sushil K. Kashaw, Rakesh K. Tekade, and Arun K. Iyer*. Nanomedicine for cancer diagnosis and therapy: advancement, success and structure activity relationship. Therapeutic Delivery, 2017 (Accepted, in press, *Corresponding Author).(Available online)
80) Samaresh Sau, Hashem O. Alsaab, Sushil Kashaw, Katyayani Tatiparti, Arun K. Iyer*. Advances in antibody drug conjugates: a new era of targeted cancer therapy. Drug Discovery Today, 2017. (Accepted, in press). (*Corresponding Author).(Available online)
79) Ketki Bhise, Sushil Kumar Kashaw, Samaresh Sau, Arun K Iyer. Nanostructured lipid carriers employing polyphenols as promising anticancer agents: Quality by design (QbD) approach. International Journal of Pharmaceutics. (Available online).
78) P Sahu, D Das, V Kashaw, AK Iyer, SK Kashaw. Nanogels: A New Dawn in Antimicrobial ChemotherapyAntimicrobial Nanoarchitectonics 2017, 101-137.
77) Prashant Sahu, Sushil K Kashaw, Varun Kushwaha, Sanyog Jain, Arun K Iyer. pH Responsive biodegradable nanogels for sustained release of bleomycin. Bioorganic & Medicinal Chemistry. (Available online).
76) Duy Luong, Prashant Kesharwani, Hashem O Alsaab, Samaresh Sau, Subhash Padhye, Fazlul H Sarkar, Arun K Iyer. Folic acid conjugated polymeric micelles loaded with a curcumin difluorinated analog for targeting cervical and ovarian cancers. Colloids and Surfaces B: Biointerfaces. (Available online).
75) Samaresh Sau, Hashem O Alsaab, Sushil Kumar Kashaw, Katyayani Tatiparti, Arun K Iyer. Advances in antibody–drug conjugates: A new era of targeted cancer. Drug Discovery Today. (Available online).
74) Samaresh Sau, Sujan Kumar Mondal, Sushil K Kashaw, Arun K Iyer, Rajkumar Banerjee. Combination of cationic dexamethasone derivative and STAT3 inhibitor (WP1066) for aggressive melanoma: a strategy for repurposing a phase I clinical trial drug. Molecular and Cellular Biochemistry. (Available online).
72) Duy Luong, Samaresh Sau, Prashant Kesharwani and Arun K. Iyer*. Polyvalent Folate-Dendrimer-Coated Iron Oxide Theranostic Nanoparticles for Simultaneous Magnetic Resonance Imaging and Precise Cancer Cell Targeting. Biomacromolecules (2017, accepted, in press)(*Corresponding Author).(Available online)
71) Prashant Sahu, Sushil K Kashaw, Sanyog Jain, Samaresh Sau, Arun K Iyer*. Assessment of penetration potential of pH responsive double walled biodegradable nanogels coated with eucalyptus oil for the controlled delivery of 5-fluorouracil: In vitro and ex vivo studies. Journal of Controlled Release. (2017 Accepted). (*Corresponding author). (Available online)
70) Hashem Alsaab, Rami Alzhrani, Prashant Kesharwani, Samaresh Sau, Sai H.S. Boddu, and Arun K. Iyer*. Folate Decorated Nanomicelles Loaded with a Potent Curcumin Analogue for Targeting Retinoblastoma. Pharmaceutics. Accepted April 2017. (*Corresponding Author).(Available online)
69) Hira Choudhury, Bapi Gorain, Manisha Pandey, Santosh Ashok Kumbhar, Rakesh Kumar Tekade, Arun K. Iyer, Prashant Kesharwani. Recent advances in TPGS-based nanoparticles of docetaxel for improved chemotherapy. International Journal of Pharmaceutics. 2017 Accepted (In press).(Available online)
68) Bapi Gorain, Muktika Tekade, Prashant Kesharwani, Arun K. Iyer, Kiran Kalia, Rakesh Kumar Tekade. The use of nanoscaffolds and dendrimers in tissue engineering. Drug Discovery Today, 2017. (Available online).
67) Kaustubh Gawde; Prashant Kesharwani; Samaresh Sau; Fazlul H Sarkar, Subhash Padhye, Sushil K Kashaw, Arun K. Iyer*. Synthesis and Characterization of Folate Decorated Albumin Bio-conjugate Nanoparticles loaded with a Synthetic Curcumin Difluorinated Analogue. Journal of Colloid and Interface Science, 2017 . *Corresponding Author. (Available online).
66) Samaresh Sau and Arun Iyer. Immune Check Point Inhibitors for the Treatment of Cancers. Special Topic in Frontiers in Pharmacology. 2017.
65) Jennifer M. Wickens, Hashem O. Alsaab, Prashant Kesharwani, Ketki Bhise, Mohd Cairul Iqbal Mohd Amin, Rakesh Kumar Tekade, Umesh Gupta and Arun K. Iyer*. Recent Advances in Hyaluronic Acid Decorated Nanocarriers for Targeted Cancer Therapy. Drug Discovery Today (2016) (*Corresponding Author).(Available online).
64) Rajkumar Patel, Madhumita Patel, Jeonghun Kwak, Arun K. Iyer, Rajshekhar Karpoormath, Jong Hak Kim. Polymeric microspheres: a delivery system for ostogenic differentiation. Polymers for Advanced Technologies. (2017, Accepted, in press).(Available online).
63) Katyayani Tatiparti, Samaresh Sau, Sushil Kumar Kashaw, Arun K Iyer*. siRNA delivery strategies: A comprehensive review of the recent developments. Nanomaterials. (*Corresponding Author) (Available online).
62) Samaresh Sau and Arun K. Iyer*. Antibody Drug Conjugates: A New Era in Personalized Medicine and Targeted Cancer Therapy. Annals of Pharmacology and Pharmaceutics. (Accepted, in Press, 2017). (*Corresponding Author) (Available online).
61) Katyayani Tatiparti, Kaustubh A. Gawde, Hashem Alsaab, Samaresh Sau, Sushil Kumar Kashaw, Prashant Kesharwani, and Arun K. Iyer*. Pancreatic Cancer – The Role of Hypoxia. Scientific Pages of Pancreatic Cancer. *Corresponding Author) (Available online).
60) Duy Luong, Prashant Kesharwani,Bryan Killinger, Anna Moszczynska, Fazlul Sarkar, Subhash Padhye, Arun K Rishi, Arun K. Iyer*. Solubility enhancement and targeted delivery of a potent anticancer flavonoid analogue to cancer cells using ligand decorated dendrimer nano-architectures. Journal of Colloid and Interface Science. 2016 Accepted, In press (*Corresponding Author) (Available online).
58) Sushil K. Kashaw and Arun K.Iyer*. Biodegradable Topical Nanogels in the Treatment of Skin and Superficial Tumors. Global Journal of Nanomedicine. 1(2): GJO.MS.ID.555552 (2017). (*Corresponding Author) (Available online).
57) Khen Eng Ng, MCIM Amim, Haliza Katas, Muhammad Wahab, Adeel M. Butt, Prashant Kesharwani, Arun K. Iyer. pH-Responsive Triblock Copolymeric Micelles Decorated with a Cell-Penetrating Peptide Provide Efficient Doxorubicin Delivery. Nanoscale Research Letters. (Accepted, In Press) (Available online).
56) Muhammad Wahab Amjad, Prashant Kesharwani, Mohd Cairul Iqbal Mohd Amin, and Arun K. Iyer.* Recent advances in the design, development, and targeting mechanisms of polymeric micelles for delivery of siRNA in cancer therapy. Progress in Polymer Science. (*Corresponding author) (Available online).
55) Mitali Mishra, Vikash K. Mishra, Varsha Kashaw, Arun K. Iyer, Sushil Kumar Kashaw. Comprehensive review on current strategies for antimalarial drug discovery. European Journal of Medicinal Chemistry 2016 (Accepted, in press) (Available online).
54) Ashok Kumar Sharma, Avinash Gothwal, Prashant Kesharwani, Hashem Alsaab, Arun K Iyer* and Umesh Gupta*. Dendrimer Nano-Architectures for Cancer Diagnosis and Anticancer Drug Delivery. Drug Discovery Today. *Corresponding author) (Available online).
53) Duy Luong, Prashant Kesharwani, Rahul Deshmukh, Mohd Cairul Iqbal Mohd Amin, Umesh Gupta, Khaled Greish, Arun K Iyer*. PEGylated PAMAM Dendrimers: Enhancing Efficacy and Mitigating Toxicity for Effective Anticancer Drug and Gene Delivery. Acta Biomaterilia (*Corresponding author) (Available online).
52) Khen Eng Ng, MCIM Amim, Haliza Katas, Muhammad Wahab, Adeel M. Butt, Prashant Kesharwani, Arun K. Iyer. pH-Responsive Triblock Copolymeric Micelles Decorated with a Cell-Penetrating Peptide Provide Efficient Doxorubicin Delivery. Nanoscale Research Letters. (Accepted, In Press) (Available online).
51) Iliyas Khan, Avinash Gothwal, Ashok Kumar Sharma, Prashant Kesharwani, Lokesh Gupta, Arun Iyer and Umesh Gupta.PLGA nanoparticles and their versatile role in anticancer drug delivery. Critical Reviews in Therapeutic Drug Carrier Systems, (Accepted, In press 2015) (Available online).
50) Muhammad Wahab Amjad, Mohd Cairul Iqbal Mohd Amin, Haliza Katas, Adeel Masood Butt, Prashant Kesharwani, Arun K. Iyer. The in vivo anti-tumor activity of folate-conjugated cholic acid-polyethylenimine micelles for the co-delivery of doxorubicin and siRNA to colorectal adenocarcinomas. Molecular Pharmaceutics, (Accepted, In press 2015) (Available online).
49) Nitin Dwivedi, Jigna Shah, Vijay Mishra, Mohd Cairul Iqbal Mohd Amin, Arun K. Iyer, Prashant Kesharwani. Dendrimer Mediated Approaches for Treatment of Brain Tumor. Journal of Biomaterials Science, Polymer Edition, (Accepted, In press 2015) (Available online).
48) Prashant Kesharwani, Lingxiao Xie, Sanjeev Banerjee, Guangzhao Mao, Subhash Padhye, Fazlul H. Sarkar, Arun K. Iyer*. Hyaluronic acid conjugated polyamidoamine dendrimers for targeted delivery of 3, 4-difluorobenzylidene curcumin for CD44 overexpressing pancreatic cancer cells. Colloids and Surfaced B: Biointerfaces, 2015 (*Corresponding author) (Available online).
47) Prashant Kesharwani, Sanjeev Banerjee, Subhash Padhye, Fazlul H. Sarkar, Arun K. Iyer*.
Hyaluronic acid engineered nano-micelles loaded with 3, 4-difluorobenzylidene curcumin for targeted killing of CD44+ stem-like pancreatic cancer cells. Biomacromolecules, 2015(*corresponding author) (Available online).
46) Prashant Kesharwani, Sanjeev Banerjee, Subhash Padhye, Fazlul H. Sarkar, Arun K. Iyer*. Parenterally administrable nano-micelles of 3, 4-difluorobenzylidene curcumin for treating pancreatic cancer, Colloids and Surfaces B: Biointerfaces. (*corresponding author) (Available online).
45) Prashant Kesharwani, Sanjeev Banerjee, Umesh Gupta, Mohd Cairul Iqbal Mohd Amin, Subhash Padhye, Fazlul H. Sarkar, Arun K. Iyer*. PAMAM Dendrimers as Promising Nanocarriers for RNAi Therapeutics. Materials Today. (2015, available online, *corresponding author) (Available online).
44) Prahsant Kesharwani and Arun K. Iyer*. Recent advances in dendrimer based nanovectors for tumor targeted drug and gene delivery. Drug Discovery Today 2015;20:536-547 (*Correspondign author) (Available online).
43) Avinash Gothwal, Prashant Kesharwani, Umesh Gupta, Iliyas Khan, Mohd Cairul Iqbal Mohd Amin, Sanjeev Banerjee, Arun K. Iyer. Dendrimers as an Effective Nanocarrier in Cardiovascular Disease. Current Pharmaceutical Design, 2015, Vol. 21. 5. (Available online).
42) Xiaoqian Yang, Arun K. Iyer, Amit Singh, Edwin Choy, Francis J. Hornicek, Mansoor M. Amiji, Zhenfeng Duan. MDR1 siRNA Loaded Hyaluronic acid-Based CD44 Targeted Nanoparticle Systems Circumvent Paclitaxel Resistance in Ovarian Cancer. Nature Scientific Reports 2015. (Available online).
41) Linlin Zhang, Arun K. Iyer^, Xiaoqian Yang, Eisuke Kobayashi, Yuqi Gou, Henry Mankin, Francis J. Hornicek, Mansoor M. Amiji, Zhenfeng Duan. Polymeric Nanoparticle-based Delivery of micro RNA-1991-3p Inhibits Proliferation and Growht of Osteosarcoma Cells. International Journal of Nanomedicine 2015, (^Equal 1st author) (Available online).
40) Xiaoqian Yang, Arun K. Iyer, Amit Singh, Lara Milane, Edwin Choy, Francis J. Hornicek, Mansoor M. Amiji, Zhenfeng Duan. Cluster of Differentiation 44 Targeted Hyaluronic Acid Based Nanoparticles for MDR1 siRNA Delivery to Overcome Drug Resistance in Ovarian Cancer. Pharmaceutical Research 2015. (Available online).
39) Ashay Jain, Prashant Kesharwani, Neeraj Kumar Garg, Atul Jain, Pradip Nirbhavane, Sanjeev Banerjee, Arun K. Iyer, Mohd Cairul Iqbal Mohd Amin. Nano-constructed Carriers Loaded With Antioxidant: Boon For Cardiovascular System. Current Pharmaceutical Design, 2015, Vol. 21. (Available online).
38) Arun K. Iyer, Zengfeng Duan and Mansoor M. Amiji. Nano-delivery Systems for Nucleic Acid Therapeutics in Drug Resistant Tumors. Molecular Pharmaceutics 2014. (Available online).
37) Arun K. Iyer, Amit Singh, Srinivas Ganta, and Mansoor Amiji. Role of integrated cancer nanomedicine in overcoming drug resistance. Advanced Drug Delivery Reviews 2013. (Available online).
36) Shardool Jain, Aatman S. Doshi, Arun K. Iyer, Mansoor M. Amiji. Multifunctional Nanoparticles for Targeting Inflammation and Cancer. Journal of Drug Targeting 2013. (Available online).
35) Shanthi Ganesh, Arun K. Iyer, David V. Morrissey, Mansoor M. Amiji. In vivo biodistribution of siRNA and cisplatin administered using CD44-targeted hyaluronic acid nanoparticles. Journal of Controlled Release 2013. (Available online).
34) Shanthi Ganesh*, Arun K. Iyer*, David V. Morrissey, Mansoor M. Amiji. Hyaluronic Acid Based Self-Assembling Nanosystems for CD44 Target Mediated siRNA Delivery to Solid Tumors. Biomaterials 2013 (*Equal first author) (Available online).
33) Shanthi Ganesh, Arun K. Iyer, Jan Weiler, David V. Morrissey, Mansoor M. Amiji. Combination of siRNA Directed Gene Silencing with Cisplatin Reverses Drug Resistance in Human Non-Small Cell Lung Cancer. Molecular Therapy Nucleic Acids, 2013. (Available online).
32) Eisuke Kobayashi, Arun K. Iyer, Francis J. Hornicek, Mansoor M. Amiji, and Zhenfeng Duan. Lipid Functionalized Dextran Nanosystems to Overcome Multidrug Resistance in Cancer: A pilot study. Clinincal Orthopeadic and Related Research 2013. (Available online).
31) Nicusor Iftimia, Arun K. Iyer, Daniel X. Hammer, Nyiom Lue, Mircea Mujat, Martha Pitman,and Mansoor Amiji. Fluorescence-guided Optical Coherence Tomography for Colon Cancer Screening: A Preliminary Mouse Study. Biomedical Optics Express 2012 (Available online).
30) Arun K. Iyer, Jiang He and Mansoor Amiji. Image-Guided Nanosystems for Targeted Delivery in Cancer Therapy. Current Medicinal Chemistry 2012. (Available online).
29) Arun K. Iyer, Xiaodong Zhu, Yang Su, Jinjin Feng, Xiaoju Zhang, Youngho Seo, Henry F. Vanbrocklin, Bin Liu and Jiang He. Novel human single chain antibody fragments that are rapidly internalizing effectively target epithelioid and sarcomatoid mesotheliomas. Cancer Research 2011. (Available online).
28) Arun K. Iyer, Yang Su, Jinjin Feng, Xiaoli Lan, Xiaodong Zhu, Yue Liu, Youngho Seo, Dongwei Gao, Henry F. VanBrocklin, V. Courtney Broaddus, Bin Liu and Jiang He. The effect of internalizing human single chain antibody fragment on liposome targeting to epithelioid and sarcomatoid mesothelioma. Biomaterials 2011. (Available online).
27) Sampath Abeylath, Srinivas Ganta, Arun K. Iyer and Mansoor Amiji. Combinatorial-Designed Multifunctional Nanosystems for Targeted Therapeutic Delivery. Accounts of Chemical Research 2011. (Available online).
26) Arun K. Iyer and Jiang He. Radiolabeled Oligonucleotides for Antisense Imaging. Current Organic Synthesis 2011 (Available online).
25) Michiro Susa*, Arun K Iyer*, Keinosuke Ryu, Edwin Choy, Francis J. Hornicek, Henry Mankin, Lara Milane, Mansoor M. Amiji, and Zhenfeng Duan. Inhibition of ABCB1 (MDR1) expression by SiRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma. PLoS ONE, 2010 (*Equal first author) (Available online).
24) Jiang He, Yong Wang, Jinjin Feng, Xiaodong Zhu, Xiaoli Lan, Arun K. Iyer, Niu Zhang, Youngho Seo, Henry F. VanBrocklin, Bin Liu. Targeting prostate cancer cells in vivo using a rapidly internalizing novel human single chain antibody. Journal of Nuclear Medicine 2010 (Available online).
23) Jun Fang, Takahiro Seki, Haibo Qin, Gahininath Y. Bharate, Arun K. Iyer, Hiroshi Maeda. Tissue Protective Effect of Xanthine Oxidase Inhibitor, Polymer Conjugate SMA-AHPP, on Hepatic Ischemia-Reperfusion Injury. Experimental Biology and Medicine 2010 (Available online).
22) Jun Fang*, Arun K Iyer*, Hideaki Nakamura, Takahiro Seki, Khaled Greish and Hiroshi Maeda. SMA-copolymer conjugate of AHPP: a polymeric inhibitor of xanthine oxidase with potential antihypertensive effect. Journal of Controlled Release, 2009 (*Equal first author). (Available online).
21) Michiro Susa, Arun K. Iyer, Keinosuke Ryu, Francis J. Hornicek, Henry Mankin, Mansoor M. Amiji, Zhenfeng Duan. Doxorubicin Loaded Polymeric Nanoparticulate Delivery System to Overcome Drug Resistance in Osteosarcoma. BMC Cancer, 2009 (Available online).
20) Jurstine Daruwalla, Khaled Greish, Cathy Malcontenti-Wilson, Vijayaragavan Muralidharan,Arun Iyer, Hiroshi Maeda and Chris Christophi. Styrene maleic acid-pirarubicin enhances tumor permeability and disrupts the microvasculature of colorectal liver metastases. Journal of Vascular Research 2009 (Available online).
19) Karoline V. Gleixner, Matthias Mayerhofer, Anja Vales, Alexander Gruze, Gregor Hörmann, Veronika Ferenc, Eva Lackner, Emir Hadzijusufovic, Michael Kneidinger, Arun K. Iyer, Maria-Theresa Krauth, Winfried F. Pickl, Brigitte Marian, Renate Panzer-Grünmayer, Christian Sillaber, Hiroshi Maeda, Christoph Zielinski, Peter Valent. Targeting of Hsp32 in solid tumors and leukemias: A novel approach to optimize anticancer therapy. Currernt Cancer Drug Targets, 2009. (Available online).
18) Emir Hadzijusufovic, Laura Rebuzzi, Karoline V. Gleixner, Veronika Ferenc, Rudin Kondo, Alexander Gruze, Michael Kneidinger, Maria-Theresa Krauth, Matthias Mayerhofer, Puchit Samorapoompichit, Khaled Greish, Arun K. Iyer, Winfried F. Pickl, Hiroshi Maeda, Michael Willmann, Peter Valent. Targeting of heat shock protein 32 (Hsp32)/heme oxygenase 1 (HO-1) in canine mastocytoma cells is associated with reduced growth and induction of apoptosis. Experimental Hematology 2008
17) Jun Fang, Dawei Deng, Hideaki Nakamura, Tereo Akuta, Qin Haibo, Arun K Iyer, Khaled Greish, Hiroshi Maeda. Oxystress inducing antitumor therapeutics via targeted delivery of PEG-conjugated d-amino acid oxidase. International Journal of Cancer 2008
(Available online).
16) Arun K Iyer. Synthesis, characterization, chemical and biological evaluation of polymeric micells of styrene maleic acid copolymer with tumor targeting capability. PhD Thesis, March 2008. (Available online).
15) Jun Fang, Hideaki Nakamura and Arun K Iyer. Tumor-targeted induction of oxystress for cancer therapy. Journal of Drug Targeting 2007. (Available online).
14) Jurstine Daruwalla, Khaled Greish, Mehrdad Nikfarjam, Ian Millar, Cathy Malcontenti-Wilson, Arun K Iyer, Chris Christophi. Evaluation of the effect of SMA- pirarubicin micelles on colorectal cancer liver metastases and of hyperbaric oxygen in CBA mice. Journal of Drug Targeting 2007 (Available online).
13) Arun K Iyer, Khaled Greish, Takahiro Seki, Shoko Okazaki, Jun Fang, Keizo Takeshita & Hiroshi Maeda. Polymeric micelles of zinc protoporphyrin for tumor targeted delivery based on EPR effect and singlet oxygen generation. Journal of Drug Targeting 2007 (Available online).
12) Arun K Iyer, Khaled Greish, Jun Fang, Ryoichi Murakami and Hiroshi Maeda. High Loading Nanosized micelles of Copoly(Styrene-Maleic Acid)-zinc protoporphyrin for the targeted delivery of a potent heme oxygenase inhibitor. Biomaterials 2007 (Available online).
11) Arun K Iyer, Khaled Greish, Jun Fang and Hiroshi Maeda. Exploiting the enhanced permeability and retention effect for tumor targeting. Drug Discovery Today, 2006 (Available online).
BOOK CHAPTERS
10) Khaled Greish, Arun K. Iyer, Fang Jun and Maeda H. Enhanced permeability and retention (EPR) effect and tumor-selective delivery of anticancer drugs in Delivery of protein and peptide drugs in cancer. Vladimir P. Torchilin eds., Imperial College Press, London, 37-52 , 2006.
9) Arun Iyer, Srinvas Ganta and Mansoor Amiji. Polymeric Nanoparticles as Target-Specific Delivery Systems. Handbook of Materials for Nanomedicine, Torchilin V and Amiji M eds. Pan Stanford Series on Biomedical Nanotechnology, World Scientific Publishing Inc., November 2009.
8) Srinvas Ganta, Arun Iyer and Mansoor Amiji, Multifunctional Stimuli-Responsive Nanoparticles for Targeted Delivery of Small and Macromolecular Therapeutics. Targeted Delivery of Small and Macromolecular Drugs, Mahato R. and Narang A. Eds. CRC press, May 2010.
7) Arun K. Iyer, Shanthi Ganesh, Qionglin Zhou and Mansoor Amiji. Multifunctional Nanosystems for RNA Interference Therapy. Biological Drug Products: Development and Strategies, Manmohan Sigh Eds., John Wiley 2013.
6) Amit Singh, Arun K. Iyer, Srinivas Ganta, and Mansoor Amiji. Multifunctional Nano-Systems for Cancer Therapy. Biomaterials for Cancer Therapeutics: Diagnosis, Prevention and Therapy. Kinam Park and Laura Overend Eds, Woodhead Publishing Inc. 2013.
5) Amit Singh, Arun K. Iyer and Mansoor M. Amiji. Polymeric Nanosystems for Integrated Image-Guided Therapy. Frontiers of Nanobiomedical Research, Vladimir P. Torchilin Eds, World Scientific Publishing Co. Pte., Singapore. (In press)
4) Lipa Shah, Arun K. Iyer, Mansoor M. Amiji. Image-Guided Targeted Delivery of Therapeutics to the Brain. Targeted Drug Delivery-Concepts and Design, Padma Devarajan and Sanyog Jain Eds, Springer publication. (In press)
3) Arun K. Iyer*, Faryal Mir, Ganesan Venkatesan. Rational Design of Multifunctional Nanoparticles for Targeted Cancer Imaging and Therapy. Genomics and Drug discovery, Nano in cancer: Linking Chemistry, Biology, and Clinical Applications in vivo. Sakharkar Eds., River Publishers (Denmark) (*Corresponding Author). (In press).
2) Arun K. Iyer, Shanthi Ganesh, and Mansoor M. Amiji. Polymeric Nano-Platforms for Tumor-Targeted Delivery of Nucleic Acid Therapies. Nano-Oncologicals: New Targeting And Delivery Approaches. María J. Alonso Eds. Controlled Release Society and Springer (In press).
1) Shanti Ganesh, Arun K. Iyer, and Mansoor M. Amiji. Combinatorial-Designed CD44-Targeted Hyaluronic Acid Nanoparticles for Targeted Delivery of Drugs and siRNA in Resistant Tumors. Update on Hyaluronic Acid for Biomedical Applications. Maurice Collins Eds., Smiters-Rapra publishing (In press).
132) Ketki Bhise, Samaresh Sau, Rami Alzhrani, Mohd A Rauf, Katyayani Tatiparti, Arun K Iyer*. Imaging the cellular components of the immune system for advancing diagnosis and immunotherapy of cancers. Materials Today Advances 2021: 10, 100138.
131) Shriya Reddy, Katyayani Tatiaparti, Samaresh Sau, Arun K Iyer*. Recent advances in nano delivery systems for blood-brain barrier (BBB) penetration and targeting of brain tumors. Drug Discovery Today 2021. (Online).
130) Tejaswi Koneru, Eva McCord, Shreya Pawar, Katyayani Tatiparti, Samaresh Sau, Arun K Iyer*. Transferrin: Biology and Use in Receptor-Targeted Nanotherapy of Gliomas. ACS Omega, 2021: 6(13), 8727–8733.
129) Shreya Pawar, Tejaswi Koneru, Eva McCord, Katyayani Tatiparti, Samaresh Sau, Arun K Iyer*. LDL receptors and their role in targeted therapy for glioma: a review. Drug Discovery Today 2021. (Online).
128) Eva McCord, Shreya Pawar, Tejaswi Koneru, Katyayani Tatiparti, Samaresh Sau, Arun K Iyer*. Folate Receptors’ Expression in Gliomas May Possess Potential Nanoparticle-Based Drug Delivery Opportunities. ACS Omega, 2021: 6(6), 4111–4118.
127) Priyanka Bose, Amit K Harit, Ratnesh Das, Samaresh Sau, Arun K Iyer, Sushil K Kashaw. Tuberculosis: current scenario, drug targets, and future prospects. Medicinal Chemistry Research, Springer, USA, 2021: 1-27.
126) Mohd Ahmar Rauf, Munazzah Tasleem, Ketki Bhise, Katyayani Tatiparti, Samaresh Sau, Arun K. Iyer*. Nano‐therapeutic strategies to target coronavirus. View, 2021: 20200155.
125) Ghazal Nabil, Rami Alzhrani, Hashem O Alsaab, Mohammed Atef, Samaresh Sau, Arun K Iyer, Hossny El Banna. CD44 Targeted Nanomaterials for Treatment of Triple-Negative Breast Cancer. Cancers, 2021: 13(4), 898.
124) Mohammad Oves, Mohd Ahmar Rauf, Fohad Mabood Husain, Mohammad Zubair, Iqbal MI Ismail, Arun Iyer. Fungal Infection: The Hidden Enemy? Diabetic Foot Ulcer, Springer, Singapore, 2021: 161-176.
123) Arun Iyer, Madeleine Frank, Susan Davies, William T Gelson. Mycophenolate mofetil-induced liver injury in a patient with aquaporin-4 antibody positive transverse myelitis. BMJ Case Reports CP 2020: 13(12), e238345.
122) Mohammad Oves, Mithunan Ravindran, Mohd Ahmar Rauf, Mohammad Omaish Ansari, Maryam Zahin, Arun K Iyer, Iqbal MI Ismail, Meraj A Khan, Nades Palaniyar. Comparing and Contrasting MERS, SARS-CoV, and SARS-CoV-2: Prevention, Transmission, Management, and Vaccine Development. Pathogens 2020: 9(12), 985.
121) Kushal Vanamala, Katyayani Tatiparti, Ketki Bhise, Samaresh Sau, Marc H Scheetz, Michael J Rybak, David Andes, Arun K. Iyer*. Novel Approaches for the Treatment of Methicillin-Resistant Staphylococcus aureus: Using Nanoparticles to Overcome Multidrug Resistance. Drug Discovery Today 2021: 26(1), 31-43.
120) Katyayani Tatiparti, Samaresh Sau, Mohd Ahmar Rauf, Arun K. Iyer*. Smart treatment strategies for alleviating tauopathy and neuroinflammation to improve clinical outcome in Alzheimer's disease. Drug Discovery Today, 2020: 25(12), 2110-2129.
119) Hashem O Alsaab, Maha S Alghamdi, Albatool S Alotaibi, Rami Alzhrani, Fatimah Alwuthaynani, Yusuf S Althobaiti, Atiah H Almalki, Samaresh Sau, Arun K Iyer*. Progress in Clinical Trials of Photodynamic Therapy for Solid Tumors and the Role of Nanomedicine. Cancers, 2020: 12 (10), 2793.
118) Mohd Ahmar Rauf, Katyayani Tatiparti, Samaresh Sau, Arun K. Iyer*. Hypoxia penetrating ultra-small nanoparticle for anti-cancer effect in Glioblastoma. Cancer Research, 2020: 80 (16 Supplement), 1721-1721.
117) Kushal Vanamala, Samaresh Sau, Shivani Naik, Arun K. Rishi, Arun K. Iyer*. Tumor multicomponent targeting nanoparticle for synergistic killing of drug resistant renal cell carcinoma. Cancer Research, 2020: 80 (16 Supplement), 2618-2618.
116) Ketki Bhise, Samaresh Sau, Mohd Ahmar Rauf, Arun K. Rishi, Arun K. Iyer*. Hypoxia-targeting prodrug approach for multimodal chemotherapy and immunogenic cell death in aggressive triple negative breast cancer. Cancer Research, 2020: 80 (16 Supplement), 6263-6263.
115) Mohammad Oves, Mohd Rauf, Mohammad Omaish Ansari, Aftab Aslam Parwaz Khan, Huda A Qari, Mohamed F Alajmi, Samaresh Sau, Arun K Iyer*. Graphene Decorated Zinc Oxide and Curcumin to Disinfect the Methicillin-Resistant Staphylococcus aureus. Nanomaterials, 2020: 10 (8), 1453.
114) Ketki Bhise, Samaresh Sau, Mohd Ahmar Rauf, Rami Alzhrani, Arun K. Iyer*. Hypoxia Targeting Nanoparticles for Immunogenic Cell Death of Triple Negative Breast Cancer. The FASEB Journal, 2020: 34 (S1), 1-1.
113) Katyayani Tatiparti, Mohd Ahmar Rauf, Samaresh Sau, Arun K. Iyer*. Carbonic Anhydrase-IX Guided Albumin Nanoparticles for Hypoxia-mediated Triple-Negative Breast Cancer Cell Killing and Imaging of Patient-derived Tumor. Molecules, 2020: 25 (10), 2362.
112) Katyayani Tatiparti, Mohd Ahmar Rauf, Samaresh Sau, Rami Alzhrani, Arun Iyer*. Ultra‐Small Biomimetic Nanoparticles for Alzheimer’s Disease Targeted Drug Delivery. The FASEB Journal, 2020: 34 (S1), 1-1.
111) Rami Alzhrani, Samaresh Sau, Amro Aboukameel, Hashem Alsaab, Asfar Azmi, Arun Iyer*. Tumor Stroma Targeting Nanoparticles Pro‐drug Approach for Treating Pancreatic Ductal Adenocarcinoma. The FASEB Journal, 2020: 34 (S1), 1-1.
110) Mehdi Azizi, Hassan Dianat‐Moghadam, Roya Salehi, Masoud Farshbaf, Disha Iyengar, Samaresh Sau, Arun K Iyer, Hadi Valizadeh, Mohammad Mehrmohammadi, Michael R Hamblin. Interactions Between Tumor Biology and Targeted Nanoplatforms for Imaging Applications. Advanced Functional Materials, 2020: 30 (19), 1910402.
109) Sushil K Kashaw, Prashant Sahu, Vaibhav Rajoriya, Pradeep Jana, Varsha Kashaw, Samaresh Sau, Arun K Iyer*. Exploring siRNA Umpired Nanogels: A Tale of Barrier Combating Carrier. Current Pharmaceutical Design, 2020:
108) Katyayani Tatiparti, Mohd Ahmar Rauf, Samaresh Sau, Arun K. Iyer*. A Biomimetic Drug Delivery System Targeting Tumor Hypoxia in Triple-Negative Breast Cancers. Applied Sciences, 2020: 10(3), 1075.
107) Ketki Bhise, Samaresh Sau, Rami Alzhrani, Arun K Iyer*. Nanoparticles for Immune Cell Reprogramming and Reengineering of Tumor Microenvironment. Cell Reprogramming for Immunotherapy, Humana, New York, NY, 2020: 211-221.
106) Prashant Sahu, Sushil K Kashaw, Samaresh Sau, Varun Kushwah, Sanyog Jain, Arun K Iyer*. Discovering pH triggered charge rebound surface modulated topical nanotherapy against aggressive skin papilloma. Materials Science and Engineering: C, 2019: 107, 110263.
105) Rami Alzhrani, Hashem O Alsaab, Alex Petrovici, Ketki Bhise, Kushal Vanamala, Samaresh Sau, Matthew J Krinock, Arun K Iyer*. Improving the therapeutic efficiency of noncoding RNAs in cancers using targeted drug delivery systems. Drug Discovery Today, 2020: 25 (4), 718-730
104) Samaresh Sau, Prashant Sahu, Sushil K. Kashaw, Arun K. Iyer. Multitasking Role of Dendrimers: Drug Delivery and Disease Targeting. Nanomedicine for the Treatment of Disease: From Concept to Application, CRC Press, 2019: 17-32.
103) Priya Singh, Mitali Mishra, Shivangi Agarwal, Samaresh Sau, Arun K Iyer, Sushil K Kashaw. Exploring the Role of Water Molecules in the Ligand Binding Domain of PDE4B and PDE4D: Virtual Screening Based Molecular Docking of Some Active Scaffolds. Current computer-aided drug design, 2019: Volume 15 (4), 334-366
102) Prashant Sahu, Sushil K Kashaw, Samaresh Sau, Varun Kushwah, Sanyog Jain, Ram K Agrawal, Arun K Iyer*. pH triggered and charge attracted nanogel for simultaneous evaluation of penetration and toxicity against skin cancer: In-vitro and ex-vivo study. International Journal of Biological Macromolecules, 2019: 128, 740-751.
101) Samaresh Sau, Rami Alzhrani, Ketki Bhise, Hashem O Alsaab, Sushil K Kashaw, Arun K Iyer*. Nanomaterials for tumor immunomodulation and overcoming current clinical challenges. Nanomedicine, 2019: (1743-5889), 14 (12), 1515.
100) Samaresh Sau, Alex Petrovici, Hashem O Alsaab, Ketki Bhise, Arun K Iyer*. PDL-1 antibody drug conjugate for selective chemo-guided immune modulation of cancer. Cancers, 2019: 11 (2), 232.
99) Prashant Sahu, Sushil K Kashaw, Samaresh Sau, Varun Kushwah, Sanyog Jain, Ram K Agrawal, Arun K Iyer*. pH Responsive 5-Fluorouracil Loaded Biocompatible Nanogels For Topical Chemotherapy of Aggressive Melanoma. Colloids and Surfaces B: Biointerfaces, 2019: 174, 232-245.
98) Sushil K Kashaw, Shivangi Agarwal, Mitali Mishra, Samaresh Sau, Arun K Iyer*. Molecular Docking Analysis of Caspase-3 Activators as Potential Anticancer Agents. Current Computer-Aided Drug Design, 2019: 15 (1), 55-66.
97) Ghazal Nabil, Ketki Bhise, Samaresh Sau, Mohamed Atef, Hossny A El-Banna, Arun K Iyer*. Nano-engineered delivery systems for cancer imaging and therapy: Recent advances, future direction and patent evaluation. Drug Discovery Today, 2019: 24 (2), 462-491.
96) Prashant Sahu, Sushil K Kashaw, Samaresh Sau, Arun K Iyer. Polylactide-co-glycolide-based Nanogel: Concept and Functions. Materials for Biomedical Engineering, Elsevier, 2019: 399-423.
95) Hashem O Alsaab, Rami Alzhrani, Atiah H Almalki, Yusuf S Althobaiti, Samaresh Sau, Arun K Iyer. Imaging tools to enhance animal tumor models for cancer research and drug discovery. Animal Models in Cancer Drug Discovery, Academic Press, 2019: 75-106.
94) Samaresh Sau and Arun K Iyer*. Immunotherapy and molecular role of T-cell in PD-1 antibody treated resectable lung cancer patients. Journal of Thoracic Disease, 2018: 10(8), 4682-4685.
93) Hashem O. Alsaab, Samaresh Sau, Rami M. Alzhrani, Vino T. Cheriyan, Lisa A. Polin, Ulka Vaishampayan, Arun K. Rishi, Arun K. Iyer*. Tumor Hypoxia Directed Multimodal Nanotherapy for Overcoming Drug Resistance in Renal Cell Carcinoma and Reprogramming Macrophages. Biomaterials 2018: 183, 280-294. (*Corresponding author).(Available online)
92) Ghazal Nabil, Ketki Bhise, Samaresh Sau, Mohamed Atef, Hossny A. El-Banna, Arun K. Iyer*. Nanoengineered delivery systems for cancer imaging and therapy: recent advances, future directions and patent evaluation. Drug Discovery Today (2018) Accepted, in press. (*Corresponding Author). (Available online)
91) Ketki Bhise, Samaresh Sau, Razieh Kebriaei, Seth A Rice, Kyle C Stamper, Hashem O Alsaab, Michael J Rybak, Arun K Iyer. Combination of Vancomycin and Cefazolin Lipid Nanoparticles for Overcoming Antibiotic Resistance of MRSA. Materials 2018. (Available online)
90) Vino Cheriyan, Hashem Alsaab, Sreeja Sekhar, Jaganathan Venkatesh, Arindam Mondal, Imran Vhora, Samaresh Sau, Magesh Muthu, Lisa Polin, Edi Levi, Gerold Bepler, Arun Iyer, Mandip Singh, Arun Rishi. A Carp-1 Functional Mimetic Compound is Synergistic with braf-Targeting in Non-Small Cell Lung Cancers. Oncotarget (Accepted, in press).(Available online)
89) Zhaoxian Wang, Samaresh Sau, Hashem O. Alsaab, Arun K. Iyer*. Image-Guided Therapy of Triple Negative Breast Cancer using CD44 Directed Delivery of Biocompatible Nanomicelles. Nanomedicne: NBM, 2018 (*Corresponding author). (Available online)
88) Samaresh Sau* ,HashemO.Alsaab, KetkiBhise, Rami Alzhrani, Ghazal Nabil , and Arun K.Iyer*. Multifunctional nanoparticles for cancer immunotherapy: A groundbreaking approach for reprogramming malfunctioned tumor evironment. Journal of Controlled Release, 2018 (*Corresponding author).(Available online)
87) Samaresh Sau* , Katyayani Tatiparti, Hashem O. Alsaab, Sushil K. Kashaw, and Arun K. Iyer*. A tumor multicomponent targeting chemoimmune drug delivery system for reprograming the tumor microenvironment and personalized cancer therapy. Drug Discovery Today, 2018 (*Corresponding author).(Available online)
86) Shivangi Agarwal, Ekta Verma, Vivek Kumar, Namrita Lall, Samaresh Sau, Arun K. Iyer, Sushil K. Kashaw. An integrated computational approach of molecular dynamics simulations, receptor binding studies and pharmacophore mapping analysis in search of potent inhibitors against tuberculosis. Journal of Molecular Graphics and Modelling, 2018. (Available online)
85) Vino T. Cheriyan, Hashem Alsaab, Sreeja Sekhar, Caitlin Stieber, Prashant Kesharwani, Samaresh Sau, Magesh Muthu, Lisa A. Polin, Edi Levi, Arun k. Iyer* and Arun K. Rishi*. A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of Renal Cell Carcinoma. Oncotarget, 2017 (*Corresponding Author).(Available online)
84) Katyayani Tatiparti, Samaresh Sau* , Kaustubh A. Gawde, and Arun K. Iyer* . Copper-Free ‘Click’ Chemistry-Based Synthesis and Characterization of Carbonic Anhydrase-IX Anchored Albumin-Paclitaxel Nanoparticles for Targeting Tumor Hypoxia. International Journal of Molecular Sciences. 2018. (*Corresponding author) (Available online)
83) Hashem Alsaab, Samaresh Sau*, Rami Alzharani, Katyayani Tatiparti, Ketki Bhise, Sushil K. Kashaw and Arun K. Iyer*. PD-1 and PD-L1 checkpoint signaling inhibition for cancer immunotherapy: mechanism, combinations and clinical outcome. Frontiers in Pharmacology. 2017, 8:561 . (*Corresponding Author).(Available online)
82) Kaustubh Gawde, Samaresh Sau, Katyayani Tatiparti, Sushil Kashaw, Mohammad Mehrohammadi, Asfar S. Azim and Arun K. Iyer*. Paclitaxel and Di-fluorinated Curcumin Loaded in Albumin Nanoparticles for Targeted Synergistic Combination Therapy of Ovarian and Cervical Cancers. Colloids and Surfaces B: Bionterfaces (2018) (*Corresponding Author) (Available online)
81) Ketki Bhise, Samaresh Sau, Hashem Alsaab, Sushil K. Kashaw, Rakesh K. Tekade, and Arun K. Iyer*. Nanomedicine for cancer diagnosis and therapy: advancement, success and structure activity relationship. Therapeutic Delivery, 2017 (Accepted, in press, *Corresponding Author).(Available online)
80) Samaresh Sau, Hashem O. Alsaab, Sushil Kashaw, Katyayani Tatiparti, Arun K. Iyer*. Advances in antibody drug conjugates: a new era of targeted cancer therapy. Drug Discovery Today, 2017. (Accepted, in press). (*Corresponding Author).(Available online)
79) Ketki Bhise, Sushil Kumar Kashaw, Samaresh Sau, Arun K Iyer. Nanostructured lipid carriers employing polyphenols as promising anticancer agents: Quality by design (QbD) approach. International Journal of Pharmaceutics. (Available online).
78) P Sahu, D Das, V Kashaw, AK Iyer, SK Kashaw. Nanogels: A New Dawn in Antimicrobial ChemotherapyAntimicrobial Nanoarchitectonics 2017, 101-137.
77) Prashant Sahu, Sushil K Kashaw, Varun Kushwaha, Sanyog Jain, Arun K Iyer. pH Responsive biodegradable nanogels for sustained release of bleomycin. Bioorganic & Medicinal Chemistry. (Available online).
76) Duy Luong, Prashant Kesharwani, Hashem O Alsaab, Samaresh Sau, Subhash Padhye, Fazlul H Sarkar, Arun K Iyer. Folic acid conjugated polymeric micelles loaded with a curcumin difluorinated analog for targeting cervical and ovarian cancers. Colloids and Surfaces B: Biointerfaces. (Available online).
75) Samaresh Sau, Hashem O Alsaab, Sushil Kumar Kashaw, Katyayani Tatiparti, Arun K Iyer. Advances in antibody–drug conjugates: A new era of targeted cancer. Drug Discovery Today. (Available online).
74) Samaresh Sau, Sujan Kumar Mondal, Sushil K Kashaw, Arun K Iyer, Rajkumar Banerjee. Combination of cationic dexamethasone derivative and STAT3 inhibitor (WP1066) for aggressive melanoma: a strategy for repurposing a phase I clinical trial drug. Molecular and Cellular Biochemistry. (Available online).
72) Duy Luong, Samaresh Sau, Prashant Kesharwani and Arun K. Iyer*. Polyvalent Folate-Dendrimer-Coated Iron Oxide Theranostic Nanoparticles for Simultaneous Magnetic Resonance Imaging and Precise Cancer Cell Targeting. Biomacromolecules (2017, accepted, in press)(*Corresponding Author).(Available online)
71) Prashant Sahu, Sushil K Kashaw, Sanyog Jain, Samaresh Sau, Arun K Iyer*. Assessment of penetration potential of pH responsive double walled biodegradable nanogels coated with eucalyptus oil for the controlled delivery of 5-fluorouracil: In vitro and ex vivo studies. Journal of Controlled Release. (2017 Accepted). (*Corresponding author). (Available online)
70) Hashem Alsaab, Rami Alzhrani, Prashant Kesharwani, Samaresh Sau, Sai H.S. Boddu, and Arun K. Iyer*. Folate Decorated Nanomicelles Loaded with a Potent Curcumin Analogue for Targeting Retinoblastoma. Pharmaceutics. Accepted April 2017. (*Corresponding Author).(Available online)
69) Hira Choudhury, Bapi Gorain, Manisha Pandey, Santosh Ashok Kumbhar, Rakesh Kumar Tekade, Arun K. Iyer, Prashant Kesharwani. Recent advances in TPGS-based nanoparticles of docetaxel for improved chemotherapy. International Journal of Pharmaceutics. 2017 Accepted (In press).(Available online)
68) Bapi Gorain, Muktika Tekade, Prashant Kesharwani, Arun K. Iyer, Kiran Kalia, Rakesh Kumar Tekade. The use of nanoscaffolds and dendrimers in tissue engineering. Drug Discovery Today, 2017. (Available online).
67) Kaustubh Gawde; Prashant Kesharwani; Samaresh Sau; Fazlul H Sarkar, Subhash Padhye, Sushil K Kashaw, Arun K. Iyer*. Synthesis and Characterization of Folate Decorated Albumin Bio-conjugate Nanoparticles loaded with a Synthetic Curcumin Difluorinated Analogue. Journal of Colloid and Interface Science, 2017 . *Corresponding Author. (Available online).
66) Samaresh Sau and Arun Iyer. Immune Check Point Inhibitors for the Treatment of Cancers. Special Topic in Frontiers in Pharmacology. 2017.
65) Jennifer M. Wickens, Hashem O. Alsaab, Prashant Kesharwani, Ketki Bhise, Mohd Cairul Iqbal Mohd Amin, Rakesh Kumar Tekade, Umesh Gupta and Arun K. Iyer*. Recent Advances in Hyaluronic Acid Decorated Nanocarriers for Targeted Cancer Therapy. Drug Discovery Today (2016) (*Corresponding Author).(Available online).
64) Rajkumar Patel, Madhumita Patel, Jeonghun Kwak, Arun K. Iyer, Rajshekhar Karpoormath, Jong Hak Kim. Polymeric microspheres: a delivery system for ostogenic differentiation. Polymers for Advanced Technologies. (2017, Accepted, in press).(Available online).
63) Katyayani Tatiparti, Samaresh Sau, Sushil Kumar Kashaw, Arun K Iyer*. siRNA delivery strategies: A comprehensive review of the recent developments. Nanomaterials. (*Corresponding Author) (Available online).
62) Samaresh Sau and Arun K. Iyer*. Antibody Drug Conjugates: A New Era in Personalized Medicine and Targeted Cancer Therapy. Annals of Pharmacology and Pharmaceutics. (Accepted, in Press, 2017). (*Corresponding Author) (Available online).
61) Katyayani Tatiparti, Kaustubh A. Gawde, Hashem Alsaab, Samaresh Sau, Sushil Kumar Kashaw, Prashant Kesharwani, and Arun K. Iyer*. Pancreatic Cancer – The Role of Hypoxia. Scientific Pages of Pancreatic Cancer. *Corresponding Author) (Available online).
60) Duy Luong, Prashant Kesharwani,Bryan Killinger, Anna Moszczynska, Fazlul Sarkar, Subhash Padhye, Arun K Rishi, Arun K. Iyer*. Solubility enhancement and targeted delivery of a potent anticancer flavonoid analogue to cancer cells using ligand decorated dendrimer nano-architectures. Journal of Colloid and Interface Science. 2016 Accepted, In press (*Corresponding Author) (Available online).
58) Sushil K. Kashaw and Arun K.Iyer*. Biodegradable Topical Nanogels in the Treatment of Skin and Superficial Tumors. Global Journal of Nanomedicine. 1(2): GJO.MS.ID.555552 (2017). (*Corresponding Author) (Available online).
57) Khen Eng Ng, MCIM Amim, Haliza Katas, Muhammad Wahab, Adeel M. Butt, Prashant Kesharwani, Arun K. Iyer. pH-Responsive Triblock Copolymeric Micelles Decorated with a Cell-Penetrating Peptide Provide Efficient Doxorubicin Delivery. Nanoscale Research Letters. (Accepted, In Press) (Available online).
56) Muhammad Wahab Amjad, Prashant Kesharwani, Mohd Cairul Iqbal Mohd Amin, and Arun K. Iyer.* Recent advances in the design, development, and targeting mechanisms of polymeric micelles for delivery of siRNA in cancer therapy. Progress in Polymer Science. (*Corresponding author) (Available online).
55) Mitali Mishra, Vikash K. Mishra, Varsha Kashaw, Arun K. Iyer, Sushil Kumar Kashaw. Comprehensive review on current strategies for antimalarial drug discovery. European Journal of Medicinal Chemistry 2016 (Accepted, in press) (Available online).
54) Ashok Kumar Sharma, Avinash Gothwal, Prashant Kesharwani, Hashem Alsaab, Arun K Iyer* and Umesh Gupta*. Dendrimer Nano-Architectures for Cancer Diagnosis and Anticancer Drug Delivery. Drug Discovery Today. *Corresponding author) (Available online).
53) Duy Luong, Prashant Kesharwani, Rahul Deshmukh, Mohd Cairul Iqbal Mohd Amin, Umesh Gupta, Khaled Greish, Arun K Iyer*. PEGylated PAMAM Dendrimers: Enhancing Efficacy and Mitigating Toxicity for Effective Anticancer Drug and Gene Delivery. Acta Biomaterilia (*Corresponding author) (Available online).
52) Khen Eng Ng, MCIM Amim, Haliza Katas, Muhammad Wahab, Adeel M. Butt, Prashant Kesharwani, Arun K. Iyer. pH-Responsive Triblock Copolymeric Micelles Decorated with a Cell-Penetrating Peptide Provide Efficient Doxorubicin Delivery. Nanoscale Research Letters. (Accepted, In Press) (Available online).
51) Iliyas Khan, Avinash Gothwal, Ashok Kumar Sharma, Prashant Kesharwani, Lokesh Gupta, Arun Iyer and Umesh Gupta.PLGA nanoparticles and their versatile role in anticancer drug delivery. Critical Reviews in Therapeutic Drug Carrier Systems, (Accepted, In press 2015) (Available online).
50) Muhammad Wahab Amjad, Mohd Cairul Iqbal Mohd Amin, Haliza Katas, Adeel Masood Butt, Prashant Kesharwani, Arun K. Iyer. The in vivo anti-tumor activity of folate-conjugated cholic acid-polyethylenimine micelles for the co-delivery of doxorubicin and siRNA to colorectal adenocarcinomas. Molecular Pharmaceutics, (Accepted, In press 2015) (Available online).
49) Nitin Dwivedi, Jigna Shah, Vijay Mishra, Mohd Cairul Iqbal Mohd Amin, Arun K. Iyer, Prashant Kesharwani. Dendrimer Mediated Approaches for Treatment of Brain Tumor. Journal of Biomaterials Science, Polymer Edition, (Accepted, In press 2015) (Available online).
48) Prashant Kesharwani, Lingxiao Xie, Sanjeev Banerjee, Guangzhao Mao, Subhash Padhye, Fazlul H. Sarkar, Arun K. Iyer*. Hyaluronic acid conjugated polyamidoamine dendrimers for targeted delivery of 3, 4-difluorobenzylidene curcumin for CD44 overexpressing pancreatic cancer cells. Colloids and Surfaced B: Biointerfaces, 2015 (*Corresponding author) (Available online).
47) Prashant Kesharwani, Sanjeev Banerjee, Subhash Padhye, Fazlul H. Sarkar, Arun K. Iyer*.
Hyaluronic acid engineered nano-micelles loaded with 3, 4-difluorobenzylidene curcumin for targeted killing of CD44+ stem-like pancreatic cancer cells. Biomacromolecules, 2015(*corresponding author) (Available online).
46) Prashant Kesharwani, Sanjeev Banerjee, Subhash Padhye, Fazlul H. Sarkar, Arun K. Iyer*. Parenterally administrable nano-micelles of 3, 4-difluorobenzylidene curcumin for treating pancreatic cancer, Colloids and Surfaces B: Biointerfaces. (*corresponding author) (Available online).
45) Prashant Kesharwani, Sanjeev Banerjee, Umesh Gupta, Mohd Cairul Iqbal Mohd Amin, Subhash Padhye, Fazlul H. Sarkar, Arun K. Iyer*. PAMAM Dendrimers as Promising Nanocarriers for RNAi Therapeutics. Materials Today. (2015, available online, *corresponding author) (Available online).
44) Prahsant Kesharwani and Arun K. Iyer*. Recent advances in dendrimer based nanovectors for tumor targeted drug and gene delivery. Drug Discovery Today 2015;20:536-547 (*Correspondign author) (Available online).
43) Avinash Gothwal, Prashant Kesharwani, Umesh Gupta, Iliyas Khan, Mohd Cairul Iqbal Mohd Amin, Sanjeev Banerjee, Arun K. Iyer. Dendrimers as an Effective Nanocarrier in Cardiovascular Disease. Current Pharmaceutical Design, 2015, Vol. 21. 5. (Available online).
42) Xiaoqian Yang, Arun K. Iyer, Amit Singh, Edwin Choy, Francis J. Hornicek, Mansoor M. Amiji, Zhenfeng Duan. MDR1 siRNA Loaded Hyaluronic acid-Based CD44 Targeted Nanoparticle Systems Circumvent Paclitaxel Resistance in Ovarian Cancer. Nature Scientific Reports 2015. (Available online).
41) Linlin Zhang, Arun K. Iyer^, Xiaoqian Yang, Eisuke Kobayashi, Yuqi Gou, Henry Mankin, Francis J. Hornicek, Mansoor M. Amiji, Zhenfeng Duan. Polymeric Nanoparticle-based Delivery of micro RNA-1991-3p Inhibits Proliferation and Growht of Osteosarcoma Cells. International Journal of Nanomedicine 2015, (^Equal 1st author) (Available online).
40) Xiaoqian Yang, Arun K. Iyer, Amit Singh, Lara Milane, Edwin Choy, Francis J. Hornicek, Mansoor M. Amiji, Zhenfeng Duan. Cluster of Differentiation 44 Targeted Hyaluronic Acid Based Nanoparticles for MDR1 siRNA Delivery to Overcome Drug Resistance in Ovarian Cancer. Pharmaceutical Research 2015. (Available online).
39) Ashay Jain, Prashant Kesharwani, Neeraj Kumar Garg, Atul Jain, Pradip Nirbhavane, Sanjeev Banerjee, Arun K. Iyer, Mohd Cairul Iqbal Mohd Amin. Nano-constructed Carriers Loaded With Antioxidant: Boon For Cardiovascular System. Current Pharmaceutical Design, 2015, Vol. 21. (Available online).
38) Arun K. Iyer, Zengfeng Duan and Mansoor M. Amiji. Nano-delivery Systems for Nucleic Acid Therapeutics in Drug Resistant Tumors. Molecular Pharmaceutics 2014. (Available online).
37) Arun K. Iyer, Amit Singh, Srinivas Ganta, and Mansoor Amiji. Role of integrated cancer nanomedicine in overcoming drug resistance. Advanced Drug Delivery Reviews 2013. (Available online).
36) Shardool Jain, Aatman S. Doshi, Arun K. Iyer, Mansoor M. Amiji. Multifunctional Nanoparticles for Targeting Inflammation and Cancer. Journal of Drug Targeting 2013. (Available online).
35) Shanthi Ganesh, Arun K. Iyer, David V. Morrissey, Mansoor M. Amiji. In vivo biodistribution of siRNA and cisplatin administered using CD44-targeted hyaluronic acid nanoparticles. Journal of Controlled Release 2013. (Available online).
34) Shanthi Ganesh*, Arun K. Iyer*, David V. Morrissey, Mansoor M. Amiji. Hyaluronic Acid Based Self-Assembling Nanosystems for CD44 Target Mediated siRNA Delivery to Solid Tumors. Biomaterials 2013 (*Equal first author) (Available online).
33) Shanthi Ganesh, Arun K. Iyer, Jan Weiler, David V. Morrissey, Mansoor M. Amiji. Combination of siRNA Directed Gene Silencing with Cisplatin Reverses Drug Resistance in Human Non-Small Cell Lung Cancer. Molecular Therapy Nucleic Acids, 2013. (Available online).
32) Eisuke Kobayashi, Arun K. Iyer, Francis J. Hornicek, Mansoor M. Amiji, and Zhenfeng Duan. Lipid Functionalized Dextran Nanosystems to Overcome Multidrug Resistance in Cancer: A pilot study. Clinincal Orthopeadic and Related Research 2013. (Available online).
31) Nicusor Iftimia, Arun K. Iyer, Daniel X. Hammer, Nyiom Lue, Mircea Mujat, Martha Pitman,and Mansoor Amiji. Fluorescence-guided Optical Coherence Tomography for Colon Cancer Screening: A Preliminary Mouse Study. Biomedical Optics Express 2012 (Available online).
30) Arun K. Iyer, Jiang He and Mansoor Amiji. Image-Guided Nanosystems for Targeted Delivery in Cancer Therapy. Current Medicinal Chemistry 2012. (Available online).
29) Arun K. Iyer, Xiaodong Zhu, Yang Su, Jinjin Feng, Xiaoju Zhang, Youngho Seo, Henry F. Vanbrocklin, Bin Liu and Jiang He. Novel human single chain antibody fragments that are rapidly internalizing effectively target epithelioid and sarcomatoid mesotheliomas. Cancer Research 2011. (Available online).
28) Arun K. Iyer, Yang Su, Jinjin Feng, Xiaoli Lan, Xiaodong Zhu, Yue Liu, Youngho Seo, Dongwei Gao, Henry F. VanBrocklin, V. Courtney Broaddus, Bin Liu and Jiang He. The effect of internalizing human single chain antibody fragment on liposome targeting to epithelioid and sarcomatoid mesothelioma. Biomaterials 2011. (Available online).
27) Sampath Abeylath, Srinivas Ganta, Arun K. Iyer and Mansoor Amiji. Combinatorial-Designed Multifunctional Nanosystems for Targeted Therapeutic Delivery. Accounts of Chemical Research 2011. (Available online).
26) Arun K. Iyer and Jiang He. Radiolabeled Oligonucleotides for Antisense Imaging. Current Organic Synthesis 2011 (Available online).
25) Michiro Susa*, Arun K Iyer*, Keinosuke Ryu, Edwin Choy, Francis J. Hornicek, Henry Mankin, Lara Milane, Mansoor M. Amiji, and Zhenfeng Duan. Inhibition of ABCB1 (MDR1) expression by SiRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma. PLoS ONE, 2010 (*Equal first author) (Available online).
24) Jiang He, Yong Wang, Jinjin Feng, Xiaodong Zhu, Xiaoli Lan, Arun K. Iyer, Niu Zhang, Youngho Seo, Henry F. VanBrocklin, Bin Liu. Targeting prostate cancer cells in vivo using a rapidly internalizing novel human single chain antibody. Journal of Nuclear Medicine 2010 (Available online).
23) Jun Fang, Takahiro Seki, Haibo Qin, Gahininath Y. Bharate, Arun K. Iyer, Hiroshi Maeda. Tissue Protective Effect of Xanthine Oxidase Inhibitor, Polymer Conjugate SMA-AHPP, on Hepatic Ischemia-Reperfusion Injury. Experimental Biology and Medicine 2010 (Available online).
22) Jun Fang*, Arun K Iyer*, Hideaki Nakamura, Takahiro Seki, Khaled Greish and Hiroshi Maeda. SMA-copolymer conjugate of AHPP: a polymeric inhibitor of xanthine oxidase with potential antihypertensive effect. Journal of Controlled Release, 2009 (*Equal first author). (Available online).
21) Michiro Susa, Arun K. Iyer, Keinosuke Ryu, Francis J. Hornicek, Henry Mankin, Mansoor M. Amiji, Zhenfeng Duan. Doxorubicin Loaded Polymeric Nanoparticulate Delivery System to Overcome Drug Resistance in Osteosarcoma. BMC Cancer, 2009 (Available online).
20) Jurstine Daruwalla, Khaled Greish, Cathy Malcontenti-Wilson, Vijayaragavan Muralidharan,Arun Iyer, Hiroshi Maeda and Chris Christophi. Styrene maleic acid-pirarubicin enhances tumor permeability and disrupts the microvasculature of colorectal liver metastases. Journal of Vascular Research 2009 (Available online).
19) Karoline V. Gleixner, Matthias Mayerhofer, Anja Vales, Alexander Gruze, Gregor Hörmann, Veronika Ferenc, Eva Lackner, Emir Hadzijusufovic, Michael Kneidinger, Arun K. Iyer, Maria-Theresa Krauth, Winfried F. Pickl, Brigitte Marian, Renate Panzer-Grünmayer, Christian Sillaber, Hiroshi Maeda, Christoph Zielinski, Peter Valent. Targeting of Hsp32 in solid tumors and leukemias: A novel approach to optimize anticancer therapy. Currernt Cancer Drug Targets, 2009. (Available online).
18) Emir Hadzijusufovic, Laura Rebuzzi, Karoline V. Gleixner, Veronika Ferenc, Rudin Kondo, Alexander Gruze, Michael Kneidinger, Maria-Theresa Krauth, Matthias Mayerhofer, Puchit Samorapoompichit, Khaled Greish, Arun K. Iyer, Winfried F. Pickl, Hiroshi Maeda, Michael Willmann, Peter Valent. Targeting of heat shock protein 32 (Hsp32)/heme oxygenase 1 (HO-1) in canine mastocytoma cells is associated with reduced growth and induction of apoptosis. Experimental Hematology 2008
17) Jun Fang, Dawei Deng, Hideaki Nakamura, Tereo Akuta, Qin Haibo, Arun K Iyer, Khaled Greish, Hiroshi Maeda. Oxystress inducing antitumor therapeutics via targeted delivery of PEG-conjugated d-amino acid oxidase. International Journal of Cancer 2008
(Available online).
16) Arun K Iyer. Synthesis, characterization, chemical and biological evaluation of polymeric micells of styrene maleic acid copolymer with tumor targeting capability. PhD Thesis, March 2008. (Available online).
15) Jun Fang, Hideaki Nakamura and Arun K Iyer. Tumor-targeted induction of oxystress for cancer therapy. Journal of Drug Targeting 2007. (Available online).
14) Jurstine Daruwalla, Khaled Greish, Mehrdad Nikfarjam, Ian Millar, Cathy Malcontenti-Wilson, Arun K Iyer, Chris Christophi. Evaluation of the effect of SMA- pirarubicin micelles on colorectal cancer liver metastases and of hyperbaric oxygen in CBA mice. Journal of Drug Targeting 2007 (Available online).
13) Arun K Iyer, Khaled Greish, Takahiro Seki, Shoko Okazaki, Jun Fang, Keizo Takeshita & Hiroshi Maeda. Polymeric micelles of zinc protoporphyrin for tumor targeted delivery based on EPR effect and singlet oxygen generation. Journal of Drug Targeting 2007 (Available online).
12) Arun K Iyer, Khaled Greish, Jun Fang, Ryoichi Murakami and Hiroshi Maeda. High Loading Nanosized micelles of Copoly(Styrene-Maleic Acid)-zinc protoporphyrin for the targeted delivery of a potent heme oxygenase inhibitor. Biomaterials 2007 (Available online).
11) Arun K Iyer, Khaled Greish, Jun Fang and Hiroshi Maeda. Exploiting the enhanced permeability and retention effect for tumor targeting. Drug Discovery Today, 2006 (Available online).
BOOK CHAPTERS
10) Khaled Greish, Arun K. Iyer, Fang Jun and Maeda H. Enhanced permeability and retention (EPR) effect and tumor-selective delivery of anticancer drugs in Delivery of protein and peptide drugs in cancer. Vladimir P. Torchilin eds., Imperial College Press, London, 37-52 , 2006.
9) Arun Iyer, Srinvas Ganta and Mansoor Amiji. Polymeric Nanoparticles as Target-Specific Delivery Systems. Handbook of Materials for Nanomedicine, Torchilin V and Amiji M eds. Pan Stanford Series on Biomedical Nanotechnology, World Scientific Publishing Inc., November 2009.
8) Srinvas Ganta, Arun Iyer and Mansoor Amiji, Multifunctional Stimuli-Responsive Nanoparticles for Targeted Delivery of Small and Macromolecular Therapeutics. Targeted Delivery of Small and Macromolecular Drugs, Mahato R. and Narang A. Eds. CRC press, May 2010.
7) Arun K. Iyer, Shanthi Ganesh, Qionglin Zhou and Mansoor Amiji. Multifunctional Nanosystems for RNA Interference Therapy. Biological Drug Products: Development and Strategies, Manmohan Sigh Eds., John Wiley 2013.
6) Amit Singh, Arun K. Iyer, Srinivas Ganta, and Mansoor Amiji. Multifunctional Nano-Systems for Cancer Therapy. Biomaterials for Cancer Therapeutics: Diagnosis, Prevention and Therapy. Kinam Park and Laura Overend Eds, Woodhead Publishing Inc. 2013.
5) Amit Singh, Arun K. Iyer and Mansoor M. Amiji. Polymeric Nanosystems for Integrated Image-Guided Therapy. Frontiers of Nanobiomedical Research, Vladimir P. Torchilin Eds, World Scientific Publishing Co. Pte., Singapore. (In press)
4) Lipa Shah, Arun K. Iyer, Mansoor M. Amiji. Image-Guided Targeted Delivery of Therapeutics to the Brain. Targeted Drug Delivery-Concepts and Design, Padma Devarajan and Sanyog Jain Eds, Springer publication. (In press)
3) Arun K. Iyer*, Faryal Mir, Ganesan Venkatesan. Rational Design of Multifunctional Nanoparticles for Targeted Cancer Imaging and Therapy. Genomics and Drug discovery, Nano in cancer: Linking Chemistry, Biology, and Clinical Applications in vivo. Sakharkar Eds., River Publishers (Denmark) (*Corresponding Author). (In press).
2) Arun K. Iyer, Shanthi Ganesh, and Mansoor M. Amiji. Polymeric Nano-Platforms for Tumor-Targeted Delivery of Nucleic Acid Therapies. Nano-Oncologicals: New Targeting And Delivery Approaches. María J. Alonso Eds. Controlled Release Society and Springer (In press).
1) Shanti Ganesh, Arun K. Iyer, and Mansoor M. Amiji. Combinatorial-Designed CD44-Targeted Hyaluronic Acid Nanoparticles for Targeted Delivery of Drugs and siRNA in Resistant Tumors. Update on Hyaluronic Acid for Biomedical Applications. Maurice Collins Eds., Smiters-Rapra publishing (In press).